Presenting the current outbreak of monkeypox big differences in symptoms versus the earlier ones recorded in endemic areas, including rectal pain or penile edema, according to a study of British patients published by the British Medical Journal.
The findings are based on 197 confirmed cases of monkeypox at a London infectious disease center between May and July 2022, and the researchers believe these findings should help doctors catch infections earlier.
The study indicates that some of the common symptoms described by sufferers, such as pain in the rectum, swelling of the penis (oedema) or tonsils, differ from those described in previous eruptions.
The participants in this study were Men with an average age of 38 years, 196 of whom reported having sex with men. All patients had skin or mucosal lesions, most commonly on the genitals or perianal area.
The majority (86%) of patients reported systemic disease (which affects the whole body) and the most common systemic symptoms were fever (62%), swollen lymph nodes (58%) and myalgia (32%).
The researchers found that, contrary to existing case reports suggesting that systemic symptoms precede skin lesions, 38% of patients developed them. after the appearance of mucocutaneous lesions.
Of the patients examined, 71 reported rectal pain, 33 sore throat, and 31 penile edema, while 27 had oral lesions, 22 had a single lesion, and nine had swollen tonsils.
Individual lesions and swollen tonsils were not known
The authors note that solitary lesions and swollen tonsils were not previously known to be typical features of monkeypox infection and could be confused with other diseases.
Only one of the study participants had recently traveled to a region where the disease is endemic, confirming this Ongoing broadcast within the UK.
Likewise, only a quarter of the patients had a known contact with someone with confirmed monkeypox infection, increasing the possibility of transmission from those with few or no symptoms.
The authors acknowledge some limitations, such as the observational nature of the results, the possible variability of clinical registries, and the fact that the data are confined to a single center, according to The British Medical Journal.
So far, 70% of the cases of this outbreak are concentrated in Europe. Spain has the highest number of cases reported in the world (3,595), followed by the United States (2,881), Germany (2,410), the United Kingdom (2,208) and France (1,567).